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Features testimonials

What are the side effects of weight loss injections?

Written by Dr Dave Reilly
wrinkle repair

Read on to discover the main side effects of weight loss injections and how to best support your health on your rapid weight loss journey.

Weight loss injections like Ozempic, Mounjaro and Wegovy have given many women something powerful - control and confidence. A quieter appetite. Clearer choices. Less mental load around food.

For a lot of Absoluters , this shift feels like the freedom they've been craving.

We spoke to real women using these injections to understand what they’re REALLY experiencing - the questions, the wins, and the side effects.

Here, we break it all down. What’s normal, what’s not, what your body’s adjusting to - and how to support it along the way with the help of our latest supplement - Sculpt Pro.


EXPERT ADVICE
“Sculpt Pro contains 30 key nutrients to help reduce the risks of the frequent side effects associated with GLP-1 medications.”
Jenna Hope Nutritionist at Absolute Collagen

8 common side effects.

Everyone’s experience is different, but when we spoke to women on GLP-1s, some side effects came up more than others…

1. Skin sagging or looseness.

Weight loss injections can lead to faster physical change than your body’s used to, and when the number on the scale drops quickly, skin doesn’t always keep pace.

That’s especially true as we get older. When collagen production naturally slows, skin can feel less firm or springy - particularly around the face, arms or stomach.

The good news? There’s plenty you can do to support your skin structure as your body adapts. Staying hydrated and getting plenty of sleep helps. So does eating enough protein and nutrients that help your body form collagen in the first place.

collagen

HOW SCULPT PRO CAN HELP?

Our 8000mg collagen and 80mg vitamin C formula is clinically proven to support skin elasticity and firmness, to help support your skin health from the inside-out.

EXPERT ADVICE
“Healthy fats, omega-3 and antioxidants are pivotal for promoting skin elasticity. Things like oily fish, walnuts, full-fat Greek yoghurt, eggs, vegetables and olive oil will all help. And of course, try to limit sugar consumption.”
Jenna Hope Nutritionist at Absolute Collagen

2. Dehydration.

It's one of the things many women don’t expect with weight loss injections.

Less appetite can also mean less thirst - and when you're eating less, you're not getting as much water from food either. It’s an easy one to miss.

The signs? Dry skin . Headaches. Fatigue. Feeling a bit off.

Sipping water regularly (not downing a glass once you remember) is the best place to start. And if you’re able to, adding electrolytes can help your body hold on to hydration - and support that all-important fluid balance.

HOW SCULPT PRO CAN HELP?

It contains a clinically-proven powerhouse of electrolytes to ensure your body gets the hydration it needs.

3. Muscle loss.

When weight comes off fast, it’s not always just fat that disappears. Without enough protein, your body can lose muscle too, leaving you feeling less strong or not quite like yourself - even if the scale says otherwise.

The fix? Think muscle, not just weight.

A little gentle movement helps. So does upping your protein - and making sure your diet includes the right nutrients to support muscle function whilst your body adjusts.

HOW SCULPT PRO CAN HELP?

Clinically proven doses of creatine and BCAAs (branched-chain amino acids) in the formula help protect lean muscle mass and support tone during a calorie deficit.

4. Low energy levels.

Feeling tired? You’re not alone. It’s completely normal to feel more tired than usual when you start GLP-1s - especially in the early days. Eating less can mean fewer calories, fewer nutrients, and less fuel to keep you going.

To help your energy bounce back, focus on steady meals, protein where you can, and staying hydrated. And don’t underestimate rest - your body’s doing a lot of work behind the scenes.

This phase won’t last forever. Your energy will even out as your routine does.

HOW SCULPT PRO CAN HELP?

It features B vitamins to improve your energy levels alongside magnesium and vitamin D3 to support quality sleep.

5. Digestive issues.

Digestive changes are one of the most common side effects of weight loss injections. That’s because GLP-1s slow the rate food leaves your stomach, which can lead to bloating, indigestion or reflux - especially after bigger meals.

To feel more comfortable, try eating slowly, spacing meals out throughout the day, and staying upright after eating.

Some women also experience diarrhoea in the early weeks. Keeping meals simple can help - think lean protein, cooked veg, and easy-to-digest carbs like white rice or toast.

HOW SCULPT PRO CAN HELP?

It includes a clinically proven combo of probiotics and inulin (fibre) to improve gut function, reduce bloating, and enhance nutrient absorption.

6. Blurred vision.

Some women reported temporary blurry vision whilst taking weight loss injections. It’s often down to dehydration or changes in blood sugar as your appetite and intake shift.

The fix can be simple: stay hydrated and eat regularly to keep things steady.

But if the blurriness sticks around - or gets worse - don’t wait. Check in with your GP to rule out anything else and give yourself peace of mind.

HOW CAN SCULPT PRO HELP?

We've added zinc and vitamin B2 to support maintenance of normal vision.

7. Hair health changes.

If you’re losing weight quickly - or cutting back on calories - some hair shedding can happen. It’s your body’s response to the stress of change, especially if you’re not getting enough protein or nutrients to support hair growth .

The good news? It’s usually temporary.

Getting enough protein, supporting your collagen levels, and sticking to a balanced diet can help your hair return to its usual cycle over time.

HOW CAN SCULPT PRO HELP?

Our 8000mg collagen and 80mg vitamin C formula is clinically proven to boost new hair growth.

8. Decreased bone density.

Significant drops in calorie intake over time can affect bone density - especially if your diet’s lacking key nutrients.

To help keep bones strong, focus on getting enough protein, vitamin D and calcium - all of which play a role in maintaining bone strength and density as your body adjusts.

HOW CAN SCULPT PRO HELP?

It includes proven doses of calcium and vitamin D to support you in maintaining your bone health.

When do side effects start?

There’s no one-size-fits-all timeline - your body adjusts in its own way. But because weight loss injections work by changing how you process hunger and digestion, many of the side effects reflect that shift, not a sudden onset.

Here’s how it tends to go:

EARLY WEEKS?

Most women notice digestive changes first. Think nausea, bloating, or a change in bowel habits - all linked to slower digestion and reduced appetite. It’s your body adapting to a new rhythm, and these symptoms often ease as things settle.

AROUND MONTHS 2-3?

Energy, hydration and physical changes become more noticeable. When you’ve been eating less for a while, your body can start to feel it - in your energy, muscle tone, and even how your skin feels. This is often when women realise how important protein, hydration and nutrient support really are.

BEYOND 3 MONTHS?

It’s more about long-term maintenance. Things like hair shedding, skin texture, or even feeling colder can pop up - especially if weight loss has been rapid. These are often linked to lower intake, and tend to improve as your routine becomes more balanced and supportive.

EXPERT ADVICE
“When taking a supplement like Sculpt Pro, consistency is key. Daily use over several weeks is essential to see and maintain the visible results.”
Dave Reilly Senior Scientist at Absolute Collagen

When to speak to a doctor.

Most side effects from GLP-1 injections are mild (even if they’re not the most comfortable) and tend to ease as your body finds its rhythm.

But, if something doesn’t feel right, trust your gut. Speak to your doctor if symptoms are:

  1. Persistent or getting worse
  2. Impacting your daily routine
  3. Making you feel concerned or unsure

That includes things like:

  1. Ongoing vomiting
  2. Signs of dehydration
  3. Severe abdominal pain
  4. Dizziness
  5. Feeling unusually sluggish after a few weeks
  6. Digestive discomfort that doesn’t improve

These situations are rare - but if they show up, it’s always worth checking in. A quick conversation can rule things out, put your mind at ease, and help you feel more confident moving forward.

Supporting your body through change.

Weight loss injections change how much you eat - but not what your body needs.

Less food often means fewer nutrients. Slower digestion can impact gut health. And faster weight loss can put extra pressure on skin, muscle and hair.

That’s where Sculpt Pro comes in. It’s not about replacing food - it’s designed to complement your diet and support your body as it adapts.

Taken twice a day, Sculpt Pro offers consistent, targeted nutritional support through every phase of change:

AM:

Supports skin, hydration and energy - helping you feel nourished and steady from the moment you wake.

PM:

Supports muscle, gut health and hormone balance - working in sync with your body’s natural overnight recovery.

Because feeling good during weight loss isn’t just about what you lose - it’s about what you hold on to: strength, structure, and support.

EXPERT ADVICE
“Supplementing with the correct nutrients at the right time of day is essential for optimising the benefits. Some nutrients such as B-vitamins and Green Tea Extract play a role in energy production and should be taken in the morning, whilst magnesium can be taken in the evening to support sleep.”
Jenna Hope Nutritionist at Absolute Collagen

Want to know more about Sculpt Pro ? or speak to our team - we’re always here to help. You can also find out more about the supplements you need to support weight loss over on our blog .


Introducing: SCULPT PRO

The UK’s 1st precision-dosed GLP-1 Total Support Supplement, developed by leading experts to support your rapid weight loss journey.

Pre-order now to be the first to access our latest innovation.

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